Highly Selective Inhibitors of HDAC6 for the Treatment of Cancers and Neurodegenerative Disease front page preview

Highly Selective Inhibitors of HDAC6 for the Treatment of Cancers and Neurodegenerative Disease

A novel structural class of highly-selective HDAC6 inhibitors. These patented small molecules have a unique non-hydroxamic acid chemical structure. The lead compound BAS-2 has been shown to inhibit glycolysis in triple ...

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Decision Markers in Symptomatic Patients at Risk of Colorectal Cancer front page preview

Decision Markers in Symptomatic Patients at Risk of Colorectal Cancer

A panel of antibodies that distinguish with high sensitivity and specificity the presence or absence of colorectal cancer in symptomatic patients. This technology has the potential to influence clinical decision making t...

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Combating Inflammation and Fibrosis in Post-Surgery Glaucoma Patients front page preview

Combating Inflammation and Fibrosis in Post-Surgery Glaucoma Patients

Glaucoma is the leading cause of irreversible blindness and post-operative inflammation and fibrosis are determining factors in the failure of 30-50% of drainage surgeries. HyAGlauc is an implantable, biodegradable medic...

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Modifying Macrophages for the Treatment of Inflammatory Diseases front page preview

Modifying Macrophages for the Treatment of Inflammatory Diseases

Macrophages are a sub-type of immune cells that are critical for fighting infection in the body through the release of inflammatory and toxic mediators. However if inflammation persists these Macrophages become destructi...

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STAR Polypeptides – Versatile Therapeutics for Drug Delivery front page preview

STAR Polypeptides – Versatile Therapeutics for Drug Delivery

Star-polymers are a new class of polymer architecture which consist of linear arms radiating from a central core. These new star Polypeptides are superior in drug delivery compared to current commercially available tech...

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